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S100A12 (Stool) ELISA


Enzyme immunoassay intended for the quantitative determination of S100A12 in stool.

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SKU: KR6938 Category:


Fecal S100A12 (Calgranulin C, EN-RAGE) is a novel non-invasive marker distinguishing inflammatory bowel disease (IBD) from irritable bowel syndrome (IBS) or healthy individuals with a high sensitivity and specificity.

Interaction of S100A12 with cellular RAGE (Receptor for advanced glycation end products) on endothelium, mononuclear phagocytes, and lymphocytes, triggered cellular activation, with generation of key pro-inflammatory mediators.
S100A12 stool concentrations can be used as an indicator of inflammation activity in Crohn‘s disease and colitis. Since S100A12 is secreted by activated neutrophils and acts as a pro-inflammatory mediator, it can be used as marker to aid in the diagnosis and therapeutic control of inflammatory bowel diseases.

  • Product Code:


  • Brand:

    Immundiagnostik AG

  • Assay Type:

    ELISA (Enzyme Immunoassay)

  • Sample Types(s):


  • Regulatory Status:

    Research Use Only