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Soluble α-Klotho ELISA


Enzyme immunoassay for the quantitative determination of human soluble α-klotho.

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SKU: JP27998 Category:


alpha-klotho (α-Klotho) was originally characterized as an aging suppressor gene.

Low α-klotho levels are often associated with age-related diseases. α-Klotho and FGF23 are the main mediators of calcium and phosphate homeostasis. Any kind of disturbance, such as a reduced or increased production of α-Klotho, leads to metabolic bone disorders. The absence of α-Klotho leads to a substantially lower bone density than usual. In addition, α-Klotho is produced exclusively in the kidneys and brain. Studies have revealed that α-klotho levels are significantly decreased in the serum at an early stage in chronic kidney disease.

  • Product Code:


  • Brand:

    TECAN (IBL International GmbH)

  • Assay Type:

    ELISA (Enzyme Immunoassay)

  • Sample Types(s):

    Serum, Plasma, Urine

  • Regulatory Status:

    Research Use Only