Description
The IDKmonitor® Etanercept free ADA ELISA for the detection of antibodies against etanercept (e.g. Enbrel®) measures free antibodies against etanercept.
Anti-TNF-alpha therapeutic antibodies are used for suppressing therapy in rheumatic patients. There is a possibility that patients under anti-TNF-alpha antibody therapy develop antibodies against the therapeutic antibodies. This might lead to severe complications, even to a systemic anaphylaxis. Therefore, regular monitoring of both the drug level and the formation of antibodies against the drug is important for optimising therapy and the associated long-term therapeutic success. Only through regular monitoring can a secondary therapy failure be recognised at an early stage and possibly prevented.