Description
BoxA 2D is the mutant form of BoxA (DNA binding domains of HMGB1 protein) in which the two cysteines are replaced with aspartic acid.
It consists of 89 amino acids and has a calculated molecular mass of approximately 10.4 kDa. BoxA 2D in migration assay cannot block the HMGB1 induced migration of fibroblasts. It contains only trace amounts of LPS (<0.4 ng/mg protein). BoxA 2D variant can be used as negative control of BoxA wt.