Description
Eosinophil-derived neurotoxin (EDN, also known as RNASE2 or Eosinophil Protein X [EPX]), plays a significant role in the prevention of virus infections.
EPN, which is released by activated eosinophilies, is a cationic glycoprotein with strong cytotoxic characteristics. It is released by the eosinophile granules in places where eosinophiles are mainly found: in the skin, lungs, urogenital and gastrointestinal tract, that is, in the organs acting as an entry point for pathogens. The accumulation of EDN in the intestine is associated with inflammation and tissue damage.
