Description
Diamine oxidase (DAO) is the body’s own enzyme that metabolises histamine.
Although DAO is essentially found in the whole body, the most important site of its action is the intestine. The enzymatic activity of DAO determines the histamine degradation speed. In the case of DAO deficiency or inhibition, incorporated or endogenous histamine cannot be degraded quickly enough, and the symptoms of histamine intolerance are presented. Millions of people suffer from gastrointestinal problems, migraine, irritations of nasal mucosa and other allergy-like symptoms after consumption of certain nutrients. Too much histamine in the body may be the reason for these wide range of symptoms.