Description
Borrelia burgdorferi, a bacterium of the Spirochaetaceae, is the etiologic agent of Lyme disease (Borreliosis),
Borreliosis is the most common disease in Europe and the USA transmitted by tics (Ixodes). IgM antibodies usually appear approximately three weeks after the infection, IgG antibodies after four to six weeks. Lyme borreliosis can be treated with antibiotics in all stages. The performance of the Borrelia IgG ELISA is important especially to detect a borreliosis even in cases showing negative 14 kDa + OspC titers and to monitor the immune status. The Borrelia IgG ELISA employs the very highly specific recombinant Borrelia burgdorferi VlsE antigen and a highly specific crude lysate antigen blend from Borrelia burgdorferi sensu strictu, B. afzelii and B. garinii and therefore determines IgG antibodies with extremely high sensitivity and specificity. Infections with all three B. burgdorferi subspecies (garinii, afzelii and sensu strictu) are detected.
