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PMN-Elastase ELISA
GASTROENTEROLOGY
Product Code: K6840

PMN-Elastase from human polymorphnuclear granulocytes is a glycoprotein of 30 kDa which belongs to the group of serine proteases.Active PMN-Elastase is released from azurophil granula of neutrophil granulocytes after irritation or disintegration. The determination of the PMN-Elastase in stool is used to record inflammatory reactions in which neutrophils are involved. Especially in Crohn’s disease the inflammatory process goes hand in hand with an increased phagocytic activity and the biological decay of the phagocytic cells, thus, leading to an increased release of PMN-Elastase and other lysosomal enzymes.
Diagnostic area GASTROENTEROLOGY

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